Osteonecrosis of the jaw in a patient receiving bisphosphonate therapy.
نویسنده
چکیده
Clinical Challenges provides readers with a forum to discuss creative clinical solutions to challenging patient care problems. Case studies or problem descriptions may be submitted with or without discussion or solutions. References, tables, fi gures, and illustrations can be included. Materials or inquiries should be directed to Oncology Nursing Forum Associate Editor Lori A. Williams, RN, DSN, OCN, AOCN, at [email protected] or Susan Moore, RN, MSN, ANP, AOCN, at [email protected]. Case Study
منابع مشابه
Jaw Osteonecrosis in Patients Receiving Oral Bisphosphonates Therapy
We describe the cases of three patients, under the care of the rheumatology service, who presented with osteonecrosis of the jaw whist on oral bisphosphonate therapy. The first case is of a 74-year-old woman with a 12 year history of sero-negative inflammatory arthritis, having been on oral steroids for 11 years, Methotrexate for the preceding 6 years, and oral bisphosphonates for 9 years. Clin...
متن کاملOsteonecrosis Related to Oral Bisphosphonate Usage: Case Report and Review of Treatment Strategies
Bisphosphonates are a class of agents used to treat osteoclast-mediated bone diseases and many neoplasm types. Osteonecrosis of the jaw is a common side effect of bisphosphonate therapy, presenting as exposed and necrotic maxillary and/or mandibular bone. In this report, we present a case of bisphosphonate-related osteonecrosis of the jaw in a patient who received oral alendronate therapy due t...
متن کاملAvascular mandibular osteonecrosis in association with bisphosphonate therapy: a report on four patients.
UNLABELLED Over the past three years, several reports have been published on jaw osteonecrosis possibly being associated with the administration of bisphosphonates. Bisphosphonates are highly active inhibitors of osteoclasts. These drugs are used for the treatment of multiple myeloma, bone resorption in the case of metastatic malignant diseases, tumor-associated hypercalcaemia, and in the treat...
متن کاملAtypical Femoral Fracture Combined with Osteonecrosis of Jaw During Osteoporosis Treatment with Bisphosphonate
Bisphosphonate, a potent anti-resorptive agent, is generally accepted as a safe, effective, well tolerated treatment for postmenopausal osteoporosis. Atypical femoral fracture (AFF) and bisphosphonate related osteonecrosis of jaw (BRONJ) are the increasing morbidities in patients treated with long term bisphosphonate. Pathogenic mechanisms of AFF and BRONJ are not fully identified and not ident...
متن کاملOral bisphosphonate use and the prevalence of osteonecrosis of the jaw: an institutional inquiry.
BACKGROUND Initial reports of osteonecrosis of the jaw (ONJ) secondary to bisphosphonate (BP) therapy indicated that patients receiving BPs orally were at a negligible risk of developing ONJ compared with patients receiving BPs intravenously. The authors conducted a study to address a preliminary finding that ONJ secondary to oral BP therapy with alendronate sodium in a patient population at th...
متن کاملProsthodontic treatment during active osteonecrosis related to radiation and bisphosphonate therapy: a clinical report.
Osteonecrosis of the jaws following the use of bisphosphonate drugs has been reported in the literature. Presently, there is limited evidence to establish guidelines for the prosthodontic management of patients with active osteonecrosis, a history of osteonecrosis, or medical history of using these medications. This clinical report reviews the current literature regarding bisphosphonate use, an...
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ورودعنوان ژورنال:
- Oncology nursing forum
دوره 34 2 شماره
صفحات -
تاریخ انتشار 2007